Opened in 1985 as a scientific project, the museum is often described as an open-air geological laboratory. Its thematic sections explore the origin, structure, and cultural role of stone - from natural formations to carved and ritual objects. This one-hour walking excursion offers a relaxed opportunity to discover a unique landscape where science, history, and nature come together. Comfortable shoes are recommended.
Price: Free
The meeting point: at the main entrance of the conference hall, Kuprevich str. 5/1
Aleksei Yantsevich, Director of the Institute of Bioorganic Chemistry, Chairman of the Organizing committee
Aleksei Trukhanov, Deputy Chairman of the Presidium of the National Academy of Sciences of Belarus
Plenary Lecture
10:30 – 11:00Vasily Grinev
Proteogenomics as a promising multiomics tool in discovery of new human proteins
Plenary Lecture
12:30 – 13:00Kiran Kulkarni
Structural insights into sequential enzymes Cr10HGO and CrIDS in secologanin biosynthesis from Catharanthus roseus
Plenary Lecture
14:00 – 14:30Yaraslau Dzichenka
AI-agents in chemistry: highway to hell or stairway to heaven
Plenary Lecture
14:30 – 15:00Suzana Jovanović-Šanta
How many tests are enough to get (more) safe drugs and supplements?
Oral Session 1 Chemo- and bioinformatics
11:00 – 11:10Dmitry Druzhilovskiy (Russia) Information system for early safety assessment of new pharmacological substances
11:10 – 11:20Frants Konstantinov (Belarus) Virtual screening of influenza A virus inhibitors targeting the hemagglutinin stem region
11:20 – 11:30Oleg Nikonov (Russia) Conformational dynamics of the β1–β2 loop in Solanum tuberosum translation initiation factor 4E and its mutant forms as a marker of the ability to bind PVY VPg
Oral Session 1 Structural Biology
11:30 – 11:40Anastasia Kryuchkova (Russia) Mechanisms of amyloid-beta molecular interactions with D-peptides
11:40 – 11:50Zhaohan Lin (China) Native morphology and composition of large dense core vesicles in adrenergic and noradrenergic neuroendocrine cells by cryo-electron tomography
11:50 – 12:00Daniil Sidorov (Russia) online Structural elements forming Zn2+- and pH- sensitivity in mirror rhodopsins
12:00 – 12:10Evgeniy Dubrovin (Russia) DNA condensation by a periodically charged surface at different ionic strength
12:10 – 12:20Ilya Klyukin (Russia) Quantum chemical study of non-covalent complexes of closo-borate anions [BnHn-1X]y− with alanine dipeptide
12:20 – 12:30Zhe Zhang (China) Structural basis for substrate recognition and inhibition of the vesicular acetylcholine transporter enables discovery of selective inhibitors
16:10 – 16:20Xiandan Chen (Belarus) online Glutamine prevents hepatic lipid accumulation by modulating lipolysis and oxidative stress
16:20 – 16:30Ilya Fateev (Russia) Enzymatic synthesis and molecular docking studies of subtituted 5-phenyl-1,2,4-triazole-3-thione deoxyribosides
16:30 – 16:40Maria Simonova (Russia) Effects of C2 and C6 substituents on cytotoxicity of purine nucleosides
16:40 – 16:50Ryhor Sivets (Belarus) Synthesis of new purine substituted 3'-fluoro-3'-deoxy-D-ribonucleosides from D-xylose
16:50 – 17:00Yaroslav Andreev (Russia) A diterpenoid of the medicinal plant Andrographis paniculata targets vanilloid site of TRPV3 channel and relieves itch
17:00 – 17:10Vasilii Graur (Moldova) online Pyruvamide 4-allylthiosemicarbazones and their 3d metal complexes: synthesis, structural characterization, and biological evaluation
17:10 – 17:20Zaret Denieva (Russia) online Natural phytoestrogen ferutinin can form transient pores in lipid membranes in the presence of Mg2+- and Ca2+-ions
Poster Session 1 27 May, Wednesday
Please click your section name to find the code of your poster:
S-1 — Vladimir Andreitsev S-2 — Nikolai Barinov S-3 — Victoria Kolesnikova S-4 — Natalia Lekontseva S-5 — Ekaterina Nikonova
Welcome Party
17:30 – 20:00Beer Session
The program will include a tasting of selected Belarusian craft beers, accompanied by a short, engaging talk from a specialist on how to appreciate different styles and flavor notes. We also plan to present a few unusual Belarusian sweets, carefully chosen to create unexpected and memorable pairings.
Location: Poster/Exhibition Area Menu: snacks and beer
Application and mechanism of herbicide safeners based on scene-oriented strategy
Plenary Lecture
11:30 – 12:00Nikolai Rostovskii (Russia) online
Carbene chemistry of 1,2,3-triazoles
! The lecture has been rescheduled for Friday, 29 May, 14:30 – 15:00
Plenary Lecture
13:00 – 13:30Alexey Sukhorukov (Russia)
New ways to make privileged heterocyclic scaffolds using N-O bond chemistry
Plenary Lecture
15:10 – 15:40Yulia Volkova (Russia)
Versatile BODIPY dyes: design, synthesis, and intracellular bioimaging
Plenary Lecture
16:10 – 16:40Marija Stojadinović (Serbia)
Beyond animal serum: sustainable biomolecules for cell culture
Oral Session 4 Organic Chemistry
10:00 – 10:10 — Lixia Zhao (China) Design, synthesis, and herbicidal evaluation of novel ester-functionalized N‑phenylphthalimide derivatives containing pyridine as protoporphyrinogen IX oxidase inhibitors
10:10 – 10:20 — Julia Panina (Russia) Gemini amphiphiles derived from monoterpenoids: membrane perturbation and antimicrobial activity
10:20 – 10:30 — Angelina Shulgina (Russia) Sydnone imine derivatives with lipoic acid: synthesis, evaluation and comparison of biological activity
10:30 – 10:40 — Dzianis Misiulia (Belarus) Preparation of 2-amino-3-cyano-4H-chromene derivatives by multicomponent reactions and the dependence of antibacterial properties in vitro on the introduced functional groups
10:40 – 10:50 — Mariia Kniazeva (Russia) Search for synthetic rutes to key derivatives for the preparation of triazole-containing peptidomimetics
10:50 – 11:00 — Marina Shagidanova (Russia) Innovative antibacterial coatings based on organosilicon derivatives of QACs
11:00 – 11:10 — Rustem Gamirov (Russia) Phytol based bis-amphiphiles for microbial flocculation and water purification
11:10 – 11:20 — Nastassia Varabyeva (Belarus) Novel benzo[1,2-d:3,4-d']diisoxazoles and their saturated analogs as anticancer agents: design, synthesis and biological evaluation
13:30 – 13:40 — Igor Shiabiev (Russia) Non-viral systems based on dendronized thiacalix[4]arenes for siRNA delivery
13:40 – 13:50 — Evgeny Pospelov (Russia) Dioximes as convenient building blocks in the synthesis of nitrogen heterocycles
13:50 – 14:00 — Vladimir Voronin (Russia) online Enhanced vinylation protocols using in situ generated acetylene for efficient synthesis of vinyl ethers
14:00 – 14:10 — Pavel Padnya (Russia) Poly(propyleneimine) dendrimers based on thiacalixarene: synthesis, cytotoxicity, and 5-fluorouracil binding
14:10 – 14:20 — Alan Akhmedov (Russia) Macrocyclic terpenoids based on pillar[5]arene: synthesis, supramolecular self-assembly, and biological activity
14:20 – 14:30 — Maria Ledovskaya (Russia) online Calcium carbide as a source of C2 unit for the synthesis of organic building blocks and heterocycles construction
14:30 – 14:40 — Nikita Shlapakov (Russia) Adaptive dynamic homogeneous Ni catalysis for derivatization of drugs and natural compounds
Poster Session 2 28 May, Thursday
Please click your section name to find the code of your poster:
18:00 – 20:00Academical Museum of Ancient Belarusian Culture
We invite you to discover the Academical Museum of Ancient Belarusian Culture - a space where the spirit of Belarus is preserved in original, carefully studied artifacts. Here, sacred icons, carved wooden sculptures, ancient tools, woven belts, ritual textiles, and traditional costumes are not simply exhibits. They are living witnesses of faith, craftsmanship, and everyday life shaped by centuries of history. This visit offers more than a museum tour. It is an encounter with the depth, mystery, and refined heritage of Belarus - a country whose history is both bright and enduring and whose cultural voice remains distinct and compelling.
Location: Center for Research of Belarusian Culture, Language and Literature, NAS of Belarus Address: Surganova str. 1/1
How to get: A transfer to the museum will be provided from the conference venue, or you may travel independently.
Transfer meeting point: near the main entrance of the conference venue, 17:00 – 17:30 For independent visitors: please meet at the museum entrance at approximately 18:00
Commercial Session
15:40 – 16:10Total Lab (Belarus)
Possibilities of using inductively coupled plasma mass spectrometry in pharmacology and toxicology
Aleksei Yantsevich, Director of the Institute of Bioorganic Chemistry, Chairman of the Organizing committee
Plenary Lecture
11:00 – 11:30Alexandr Migas (Belarus)
High-throughput functional screening of CAR libraries in cell-based systems for optimization of antigen-binding and signaling domains
Plenary Lecture
14:00 – 14:30Herman Dorohost (Belarus) online High effective solutions for the scientifical calculations (the exact title will be later)
Plenary Lecture
14:30 – 15:00Nikolai Rostovskii (Russia) online
Carbene chemistry of 1,2,3-triazoles
Oral Session 6 Pharmacology and Toxicology
11:30 – 11:40 — Maksim Baranov (Russia) Head-to-head comparison of lentiviral and non-viral mRNA-based anti-CD19 CAR-T cells with clinically validated CD28ζ and 4-1BBζ costimulatory domains: in vitro evaluation and exploratory in vivo studies
11:40 – 11:50 — Darya Makeyeva (Belarus) Study of the effect of oligopeptide V-5 on neuromuscular parameters of C57B1/6 mice under the conditions of the rotarod performance test
11:50 – 12:00 — Vladislav Sepp (Russia) Assessment of the impact of amino acids on the rheological properties of hyaluronic acid gel
12:00 – 12:10 — Tatiyana Serebryanskaya (Belarus) Two-faced Janus: Asymmetric acyclic diaminocarbene Pd complexes as dual-active antiproliferative agents against oxaliplatin-resistant colorectal HCT116 cell line
12:10 – 12:20 — Sergei Sorokin (Russia) online Ultrafiltration cleaning of the cultured fluid of Coprinopsis lagopides fungus with fibrinolytic properties
12:20 – 12:30 — Olga Golovanova (Russia) The role of a polyelectrolyte complex based on sodium alginate and chitosan in the creation of biocomposites for orthopedics
12:40 – 12:50 — Nadezhda Aksenova (Russia) The effect of amphiphilic polymers on the photodynamic activity of methylene blue in vitro and in vivo experiments
Oral Session 7 Biochemistry
15:00 – 15:10 — Evgenii Borisenko (Russian) Novel hydroxamic acid derivatives as promising HDAC6 inhibitors with neuroprotective effect
15:10 – 15:20 — Joseph Mikhel (Russian) Identification of secreted form of thioredoxin in culture fluid of antagonistic strain Bacillus subtilis VIZR M22
15:20 – 15:30 — Veronika Novikova (Russian) Tetranitrosyl iron complexes with thiophenol derivatives: interaction with mucin
15:30 – 15:40 — Alexey Shnitko (Russian) online Making the invisible visible: determination of biologically active compounds with low UV-activity by capillary electrophoresis
15:40 – 15:50 — Mariia Chicheva (Russian) New perspective iron-sulfur nitrosyl complex as potential anti-inflammatory agent
Final of Best Poster Contest
10:00 – 11:00
Best Poster Contest. Stage 2
10 short 5-minute presentations In this session, the authors of the 10 posters selected by the Scientific Committee during the Stage 1 of the Best Poster Contest will present their work in short 5-minute talks.
Award Ceremony
15:50 – 16:20
Join us for the announcement and celebration of the winners of the Best Graphical Abstract and Best Poster Contests!
After several days of science, discussions, careful evaluation, and difficult decisions, it is finally time for applause, certificates, and a well-deserved moment of scientific glory.